The Endocannabinoid System

The Endocannabinoid System

The Endocannabinoid System (ECS) is a system of receptors that is located throughout the body. The ECS is responsible for regulating the body. It does this by communicating with just about every system in the body. Including everything for the nervous system, immune system, and organs. The goal of this system is to achieve what is called homeostasis, or balance in the body.

Cannabinoids are anything that interact with these cannabinoid receptors.  CBD is one of the primary cannabinoids found in hemp.

The ECS plays a pivotal role in the physiological processes such as mood, memory and discomfort.  There are two main cannabinoid receptors (CB1 and CB2 receptors) that are located throughout the body.

Cannabinoid Receptors

The cannabinoid receptor is the way to unlock the power of the endocannabinoid system

CB1 receptors are located throughout the body, but can primarily be found throughout the brain, spinal cord, and central nervous system.

CB1 receptors play a key role in brain function. They influence memory processing, motor regulation, discomfort sensation, mood, and sleep.

CB2 receptors are primarily found in the immune system. By activating CB2 receptors you can fight inflammation, which plays a key role in reducing discomfort.

How do These Receptors Work?

Cannabinoids interact with these CB Receptors to help coordinate and regulate how we feel and think.  Think of it as a key and lock system.  In order to activate the receptor, you need the right key.  Cannabinoids act as the key to the cannabinoid receptors lock.  Linking activates the receiving neuron into action, triggering a set of events to pass along the message and carry out a variety of cellular responses needed for homeostasis.

Why Don’t More People Know About the ECS

We have known about the ECS for about 25 years now, 1st discovered by L.A. Matsuda in the 1990’s. Matsuda was the 1st to describe the structure of and functional expression of CB1 receptors. This discovery was made because we were interested in what effects THC had on the body. They ended up discovering one of the most complex systems in the body.

Since then other cannabinoids and cannabinoid receptors have been identified and it is becoming more and more apparent everyday how vast and complex this system is. We’ve also discovered that we make our own cannabinoids, called endocannabinoids. The first endocannabinoid discovered was Anandamide. Anandamide acts on both CB-1 and CB-2 receptors and is the body’s bioequivalent to THC.

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